Interferon Gamma Release Assay for the Identification of Latent Tuberculosis Infection in Rural and Remote Settings

نویسندگان

چکیده


 There is a lack of evidence on the clinical utility interferon gamma release assay for identifying latent tuberculosis infection in rural and remote settings.
 In Indigenous communities with known history bacillus Calmette-Guérin vaccination, more positive tests results were reported tuberculin skin test than assay.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis

BACKGROUND Accurate diagnosis and subsequent treatment of latent tuberculosis infection (LTBI) is essential for TB elimination. However, the absence of a gold standard test for diagnosing LTBI makes assessment of the true prevalence of LTBI and the accuracy of diagnostic tests challenging. Bayesian latent class models can be used to make inferences about disease prevalence and the sensitivity a...

متن کامل

Interferon-gamma release assay for detection of latent tuberculosis infection in casual and close contacts of tuberculosis cases.

The tuberculin skin test (TST) has many limitations for the diagnosis of latent tuberculosis (TB infection. The aim of this study in Egypt was to estimate the usefulness of an interferon-gamma release assay (IFN-gamma) assay for the detection of latent TB infection in contacts of active TB cases. A total of 116 participants were enrolled and divided into 3 groups: community controls, casual (la...

متن کامل

Feasibility of latent tuberculosis infection diagnosis by interferon-γ release assay remote from testing facilities.

Although the tuberculin skin test (TST) has been the mainstay of the diagnosis of latent tuberculosis infection (LTBI) for many decades, interferon-gamma release assays (IGRAs) are gaining acceptance and are more specific for this diagnosis. The characteristics of one such IGRA, the QuantiFERON-TB Gold Whole Blood In-Tube, make it feasible for use in a remote setting. This study performed 62 IG...

متن کامل

Performance of an interferon-gamma release assay to diagnose latent tuberculosis infection during pregnancy.

OBJECTIVE To evaluate an interferon (IFN)-gamma release assay in diagnosing latent tuberculosis infection in pregnant adolescents and women at risk for exposure to Mycobacterium tuberculosis. METHODS This was a prospective study of women and adolescents receiving health care at Bellevue Hospital Outpatient Clinics in New York City. Each patient was assessed for M tuberculosis risk factors, ha...

متن کامل

Cost-effectiveness of interferon-gamma release assay testing for the treatment of latent tuberculosis.

The aim of the present study was to assess the cost-effectiveness of the new T-SPOT.TB assay versus the tuberculin skin test (TST) for screening contacts for latent tuberculosis (TB) infection in Switzerland. Health and economic outcomes of isoniazid treatment of 20- and 40-yr-old close contacts were compared in a Markov model over a 20-yr period following screening with TST only (at three cut-...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Canadian journal of health technologies

سال: 2021

ISSN: ['2563-6596']

DOI: https://doi.org/10.51731/cjht.2021.54